Since April 2011, the InVS has implemented an application that allows the Cire to access real-time data from mandatory reports in their region for these five notifiable diseases. The Cire has established automated analysis procedures to produce regional epidemiological reports and monitor epidemic outbreaks.The Cire Centre publishes a biannual thematic epidemiological report on these five notifiable diseases; here is the third edition, covering the first half of 2013. These epidemiological reports are based on data that has not yet been consolidated, and minor variations may be noted compared to the detailed analyses we produce separately using databases that are verified and corrected annually.