Interim vaccine effectiveness against influenza virus among outpatients, France, October 2025 to January 2026
In Europe, the 2025/26 seasonal influenza epidemic started in October 2025. Co-circulation of A(H3N2) and A(H1N1)pdm09 was observed in several countries including France. We estimated early vaccine effectiveness (VE) against influenza virus in French outpatients (5,451 positives/18,816 negatives). A significant VE across all age groups was measured: 28% (95% CI: 17-37) for those aged ≥ 65 years, 45% (95% CI: 36-53) for 18-64-year-olds and 57% (95% CIs: 29-74) for 0-17-year-olds. Reinforcing vaccination uptake is warranted.
Author(s): De Clercq Allan, Blanquart François, Vieillefond Vincent, Visseaux Benoit, Jacques Alexandra, Haim-Boukobza Stéphanie, Wehrle Valentin, Deleglise Guillaume, Duret Thomas, Bernard-Stoecklin Sibylle, Perez-Bercoff Danielle, Oblette Antoine, Lina Bruno, Rameix-Welti Marie Anne, Josset Laurence, Enouf Vincent, Bal Antonin
Publishing year: 2026
Pages: 5-11
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