Using data from the occupational disease surveillance program for the period 2007–2012, the authors compared the prevalence of work-related musculoskeletal disorders (MSDs) among truck drivers with that of other similar occupational groups. From 2007 to 2012, there was a decrease in MSDs of the lumbar spine, which could be attributed to measures to prevent exposure to whole-body vibrations. However, the number of MSDs of the cervical-dorsal spine remained the same, as these are more often linked to postural stressors than to vibrations. The risk of cervical-dorsal spine disorders is higher among male drivers compared to other occupational groups; therefore, postural stressors associated with driving or other tasks performed must be minimized.