Key Points

• Decrease in all-cause mortality in 2023 in Nouvelle-Aquitaine following the spike observed in 2021 linked to the COVID-19 pandemic;

• Male mortality remains higher than female mortality (standardized mortality rate of 1,040 per 100,000 inhabitants vs. 626 per 100,000 inhabitants);

• the leading causes of death in Nouvelle-Aquitaine are tumors and diseases of the circulatory system, for both men and women, consistent with national trends;

• Regional disparities persist, with a higher age-standardized mortality rate in Dordogne, Charente, and Creuse, the latter department having had the region’s most unfavorable mortality indicators for over 20 years.