Background: Long-term indicators of mental health are scarce in France, and suicidal behavior is often assessed solely based on suicide mortality. Methods: The epidemiological value and methodological limitations of four medical-administrative databases, from which data on suicide attempts could be extracted, were examined in the Nord-Pas-de-Calais region (France): calls to the emergency medical service (Samu) for suicide attempts (2009–2011), hospital emergency department visits with a diagnosis of suicide attempt (2012), medical-surgical hospitalizations for suicide attempts (2009–2011), and psychiatric care with a diagnosis of suicide attempt (2011). Results: one in two emergency medical services (Samu), five out of 30 emergency departments, and all medical-surgical and psychiatric units provided usable data. In the latter two sources, a unique anonymous identifier allowed for statistics at the individual level; whereas in the first two sources, the data pertains only to suicidal acts. In 2011, the rate of calls for suicide attempts per 100,000 inhabitants was 304, while the hospitalization rate with this diagnosis was 275. The highest rates were observed among men aged 20 to 49; and among women under 20 and aged 40 to 49. There is a high degree of consistency across sources regarding the average age (between 37.8 and 38.5 years) and gender (55.0% to 57.6% women). In 2011, the number of patients diagnosed with a suicide attempt and treated in psychiatry was 2.6 times lower than the number of people hospitalized in medical-surgical wards for a suicide attempt (3,563 vs. 9,327). Conclusion: The continuous collection of data and the large volume of recorded information support the use of these medical-administrative databases in the context of defining and evaluating mental health policies. However, increased participation by emergency medical services (EMS) and emergency departments, as well as improved coding of the suicidal nature of poisonings by certain services that are clearly underreporting, is necessary to improve this multi-source information system.