Objective: The analysis of mortality data is essential for public health surveillance. Given that deaths are often attributable to multiple diseases, this article presents a new method for re-estimating cause-specific standardized mortality rates by accounting for multiple causes per death. Method: Using data from the national cause-of-death database for 2010, we calculated cause-specific standardized mortality rates using: the initial cause of death and two multiple-cause weighting (MCW) strategies, which assign weights to the various causes listed on the death certificate. For each death, the sum of the weights equals 1. Thus, the influence of each death on mortality rates remains the same. The relative changes in age-standardized mortality rates according to the two MCS strategies compared to the rates obtained using the single-cause method were calculated. Results: The use of a weighting strategy significantly altered the distribution of standardized rates by cause. The relative variation in the standardized mortality rate obtained using the second PCM strategy exceeded 20% for five disease categories: genitourinary, hematological, endocrine, dermatological, and mental disorders. Conclusion: This new weighting method allows for the full utilization of the medical causes listed on the death certificate to account for the multifactorial nature of mortality and thus obtain cause-specific mortality indicators that are more relevant for public health.