BACKGROUND: Swine farmers are at increased risk of zoonotic influenza virus transmission. In France, seasonal influenza vaccination is recommended for swine farmers, yet little is known about vaccine uptake in this at-risk group. OBJECTIVES: To assess seasonal influenza vaccination uptake, its determinants, and associated attitudinal factors among swine farm managers in Brittany during the 2023-2024 influenza season. METHODS: A cross-sectional survey was conducted among a random sample of swine farm managers. Data were collected using a standardized questionnaire, including attitude items according to the French 7C-model of psychological antecedents of vaccination. RESULTS: Among 735 respondents, 14.0% [11.8%-16.4%] declared they have been vaccinated for the 2023-2024 season, and 35.0% [32.1%-38.0%] were unaware of the national recommendation. Only 33.5% demonstrated a knowledge score above 2/4. Vaccine uptake was significantly associated with older age, prior severe influenza (OR: 3.29 [1.97-5.50]), and receiving a vaccination voucher from the agricultural social security system (OR: 2.76 [1.66-4.59]). However, only 31.8% [28.6%-34.8%] reported having received one. Five among the seven components of the 7C-model were associated with vaccine uptake.Unvaccinated unwilling to vaccinate were characterised by low collective responsibility (R(2) = 16.98%) and unfavourable benefit-risk calculation (R(2) = 16.84%), while unvaccinated willing to vaccinate were mainly influenced by vaccine accessibility (R(2) = 17.32%) and negative social conformism (17.20%). CONCLUSION: Seasonal influenza vaccination uptake among swine farm managers is low. Targeting this population through tailored strategies is essential. These findings are relevant nationally and internationally and can inform One Health coordinated prevention efforts for professionals exposed to zoonotic influenza viruses.